The cartoon begins with a man carrying a Painte Blanc of white paint while singing. At the same time Penelope Pussycat is being chased by a dog. The man collides with the two animals and his machines causes Penelope to get a white-stripe. Penelope runs off while the man and the dog are left to be covered in white paint. The man kicks the dog. Penelope is revealed to be hiding near a rock. The scenario changes to a couple of ships being hosted up. Inside one of these ships Pepé Le Pew is staying. His smell and appearance terrifies the man on the ship. He pulls the anchor down and runs on air attempting to get away. Pepe emerges from the water and spots what he believes to be a female skunk (actually Penelope with a white stripe down her back). He runs straight out of the water and attempts to hold her. She runs right out of him, but Pepe grabs a hold of her tail. Pepe hits a wall, and sits down on the sand, proclaiming that there are plenty of other fish in the ocean. He decides to get up and chase after Penelope. Penelope hides next to a stone wall. Pepe emerges from the sand and Penelope reacts by running off. As she's running Pepe runs right out of the sand and proclaims that the two should get married. Penelope escapes from Pepe and he falls right off some rocks and lands into the water. Penelope is now hiding behind a tree. Pepe emerges from the water and grabs Penelope. He starts kissing her, until he notices that she looks pale. He goes into the water, and runs to a house where he gets a glass of water. When he gets back he finds that she's missing. Penelope runs near two motor-boats and gets into one. Pepe wearing a sailor's hat and smoking is right next to her. He smokes out a heart, and proceeds to jump right next to her. She escapes and hopes to get off the boat by using a scuba-tank. She jumps into the water. While there she doesn't notice it, but Pepe is also in the water with her. He grabs her under the water and kisses her. A shark approaches and Pepe hides Penelope inside a clam, so he can fight the shark alone. The shark swallows him but Pepe manages to escape thanks to his smell. The smell scares the shark so much that he runs right out of the water screaming. Pepe goes to check up on Penelope, but finds that she has vanished. He gets out of the water. Penelope is revealed to have been hiding and simply tricked Pepe so she could get away. She reaches the surface and sees an island. She gets off there, as she does Pepe reveals himself. She runs off but Pepe chases her around the Island as the camera zooms away revealing the rock on the island to look like a heart.
On CBS' version for The Bugs Bunny/Road Runner Show, the part after the dog chases Penelope Pussycat, in which the street painter asks the dog in fractured French why he crashed into him, followed by the man violently kicking the dog down the road was cut.
At the beginning of the episode, Penelope's tail looked to be thicker. But any instance afterwards and its really thin, like a normal cats tail.