The show follows the adventures of Plucky Duck, a teen-aged university student whose mentor is Daffy. Like Daffy, Plucky's exploits are often quests for fame or fortune.
Thirteen episodes were produced for the series, with all but one recycled from Tiny Toons. See the List of The Plucky Duck Show episodes.
Being largely recycled, the cast is the same as in the source, Tiny Toon Adventures.