Sugar and Spies is a 1966 Road Runner cartoon. It is the second of two Road Runner shorts directed by Robert McKimson and the only one to feature music by Walter Greene. It is also the final appearance of the Road Runner and Wile E. Coyote in the original theatrical Looney Tunes shorts.
During one of his many chases with the Road Runner, Wile E. Coyote is hit with a briefcase thrown from a crook's car in a police chase. The briefcase is actually a spy kit containing gadgets that Wile E. tries to use on the Road Runner, but which all fail as usual, including:
Sleeping gas: Road Runner dodges the gas and blows it back at Wile E., who sleepwalks off a cliff. The Road Runner places the alarm clock right beside the hole at the bottom of the gorge. Wile E. simply puts a hand out to shut it off.
Do-it-yourself time bomb that Wile E. mails to the Road Runner (to nowhere particular), but is returned to the Coyote by Road Runner (disguised as a mailman) for insufficient postage. As Wile E. takes the package back into his cave for an extra stamp, BOOM!
Explosive putty which is applied under a huge bolder with a mound of bird seed placed nearby. Wile E. hides behind another boulder farther away and lights the fuse, only to be crushed by the flying boulder.
Spy car equipped with machine guns, ejection seat and cannon: The bullets from the machine guns ricochet off a bolder and blow away the car top, the Coyote ejects himself from the car while suspended upside down, and the force from the cannon sends the car backwards, running over the Coyote who then tries to dodge the cannonball.
Remote control flying bombs: Wile E. tests the first bomb on a cactus, then sets the remote control for the next bomb to follow Road Runner, who hides under the Coyote's stool and escapes in time for Wile E. to take the explosion. When the smoke clears, the dazed Coyote has the bomb's wings attached to his arms, prompting the Road Runner to set the remote control for the moon.