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Miles Laboratories was founded as the Dr. Miles Medical Company in Elkhart, Indiana, in 1884 by Franklin Miles, a specialist in the treatment of eye and ear disorders, with an interest in the connection of the nervous system to overall health. Miles operated as an independent firm from 1884 until 1979 and as a wholly owned subsidiary of Bayer AG from 1979 until 1995, when it was consolidated into the parent corporation.
In 1985, Miles Laboratories produced a series of Bugs Bunny Vitamins.