Scooby-Doo & Shaggy Rogers are the two main characters of Hanna-Barbera's Scooby-Doo franchise. They have a cameo appearance in Looney Tunes Back in Action, in which they scold Matthew Lillard for making Shaggy "sound like a total space cadet" while portraying him in the live-action Scooby-Doo film, and Shaggy threatens to come after Lillard if he does it again in Scooby-Doo 2 Monsters Unleashed.
In this cameo, Scooby-Doo was voiced by Frank Welker while Shaggy was voiced by Casey Kasem, his original voice actor since 1969.
The duo also made cameos in Space Jam A New Legacy along with Fred Jones, Velma Dinkley and Daphne Blake as spectators to a basketball game between the Toons and the Goon Squad.